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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARNT2Aryl hydrocarbon receptor nuclear translocator 2 isoform X1. (720 aa)    
Predicted Functional Partners:
EPAS1
Endothelial PAS domain-containing protein 1 isoform X1.
   
0.891
NPAS3
Neuronal PAS domain-containing protein 3 isoform X1.
    
0.890
HIF1A
Hypoxia-inducible factor 1 alpha.
   
0.886
LOC107207636
Aryl hydrocarbon receptor-like.
   
0.801
ENSPMJP00000007662
annotation not available
   
 0.801
AHR
Aryl hydrocarbon receptor.
   
0.801
AHRR
Aryl hydrocarbon receptor repressor.
   
0.756
SIM1
Single-minded homolog 1 isoform X1.
    
 
0.685
SIM2
Single-minded homolog 2 isoform X1.
    
 
0.685
EP300
Histone acetyltransferase p300 isoform X1.
    
 0.681
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.