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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXL4F-box and leucine-rich repeat protein 4. (620 aa)    
Predicted Functional Partners:
SKP1
S-phase kinase-associated protein 1.
   
 0.835
CUL1
Cullin-1 isoform X1.
    
 0.785
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.693
LOC107199423
NEDD8-like.
    
 0.684
CUL3
Cullin 3.
    
 0.655
COMMD5
COMM domain-containing protein 5 isoform X1.
     
 0.640
ELOC
Transcription elongation factor B polypeptide 1.
    
 0.618
NAE1
Amyloid beta precursor protein binding protein 1.
     
 0.617
UBA3
NEDD8-activating enzyme E1 catalytic subunit isoform X1.
     
 0.617
UBE2F
Ubiquitin-conjugating enzyme E2 F.
    
  0.615
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.