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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TXNDC17Thioredoxin domain-containing protein 17. (273 aa)    
Predicted Functional Partners:
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2.
   
  
 0.695
CLPX
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial isoform X1.
      
 0.537
TXN
Thioredoxin 1.
   
  
 0.531
AKR1A1
Alcohol dehydrogenase [NADP(+)] isoform X1.
   
  
 0.508
NDUFAB1
NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein.
   
  
 0.493
ATP5MD
Up-regulated during skeletal muscle growth protein 5.
   
  
 0.488
TXN2
Thioredoxin, mitochondrial.
   
  
 0.455
ENSPMJP00000021497
annotation not available
    
 
 0.452
CYB5R4
Cytochrome b5 reductase 4 isoform X1.
      
 0.432
NME8
Thioredoxin domain-containing protein 3.
   
  
 0.427
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.