Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIVA1SIVA1 apoptosis inducing factor. (217 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen.
    
 
 0.910
RAD18
E3 ubiquitin-protein ligase RAD18.
    
 
 0.886
XIAP
E3 ubiquitin-protein ligase XIAP isoform X1.
    
 
 0.862
MDM2
E3 ubiquitin-protein ligase Mdm2 isoform X1.
    
 
 0.737
CASP6
Caspase 6.
      
 0.680
BCL2L1
Bcl-2-like 1 (apoptosis regulator Bcl-X).
    
 
 0.672
FOXE1
Forkhead box E3.
      
 0.636
STMN1
Stathmin.
    
 
 0.630
CDCA4
Cell division cycle associated 4.
   
  
 0.574
TMEM121
Transmembrane protein 121.
      
 0.555
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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