close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JUPJunction plakoglobin. (758 aa)    
Predicted Functional Partners:
APC
Adenomatous polyposis coli protein isoform X1.
   
 0.948
CTNNB1
Catenin beta-1 isoform X1.
  
 
0.944
GSK3B
Glycogen synthase kinase-3 beta isoform X1.
    
 0.935
CTNNBIP1
Beta-catenin-interacting protein 1 (inhibitor of beta-catenin and Tcf-4).
    
 0.932
LEO1
RNA polymerase-associated protein LEO1 isoform X1.
    
  0.924
CDH5
Cadherin 5, type 2, VE-cadherin.
    
 0.913
SKP1
S-phase kinase-associated protein 1.
   
 0.887
PKP2
Plakophilin 2.
   
 0.865
DSC1
Desmocollin-1 isoform X1.
   
 0.862
CSNK1A1
Casein kinase I isoform X1.
   
 0.861
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.