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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLIN1Perilipin-1. (590 aa)    
Predicted Functional Partners:
PLIN2
Perilipin-2 isoform X1.
     
0.910
ABHD5
1-acylglycerol-3-phosphate O-acyltransferase ABHD5.
   
 0.765
VAMP3
Vesicle-associated membrane protein 3.
   
  0.552
RABEPK
Rab9 effector protein with kelch motifs.
    
  0.547
IGF2R
Cation-independent mannose-6-phosphate receptor.
   
 0.529
AP2M1
AP-2 complex subunit mu isoform X1.
    
  0.515
RHOBTB3
Rho-related BTB domain-containing protein 3-like.
    
 0.512
ADIPOQ
Adiponectin isoform X1.
   
  
 0.485
AP2A2
AP-2 complex subunit alpha-2 isoform X1.
    
  0.464
LOC107209691
C-X3-C motif chemokine 1.
  
  0.458
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.