close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTSLCathepsin L1 isoform X2. (338 aa)    
Predicted Functional Partners:
LOC107214698
Cathepsin S-like.
  
 
0.937
BID
BH3-interacting domain death agonist isoform X1.
   
 
 0.907
BCL2
Apoptosis regulator Bcl-2.
   
 
 0.905
BCL2L1
Bcl-2-like 1 (apoptosis regulator Bcl-X).
     
 0.902
LOC107208235
Cystatin-A-like.
   
 0.824
CD74
HLA class II histocompatibility antigen gamma chain isoform X1.
   
 0.711
BIRC2
Baculoviral IAP repeat-containing protein 2/3.
     
 0.668
XIAP
E3 ubiquitin-protein ligase XIAP isoform X1.
     
 0.662
LOC107207386
Baculoviral IAP repeat-containing protein 5.1-like.
     
 0.660
LOC107202602
Baculoviral IAP repeat-containing protein 5-like.
     
 0.660
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.