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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GNAO1Guanine nucleotide-binding protein G(o) subunit alpha isoform X1. (354 aa)    
Predicted Functional Partners:
FZD4
Frizzled 4.
    
 0.937
FZD6
Frizzled 6.
    
  0.937
FZD3
Frizzled 3.
    
  0.932
PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1.
   
 0.930
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1.
   
 0.927
FZD2
Frizzled 2.
    
  0.925
FZD1
Frizzled 1/7.
    
  0.925
FZD7
Frizzled 1/7.
    
  0.925
FZD10
Frizzled 9/10.
    
 0.924
FZD9
Frizzled 9/10.
    
 0.924
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.