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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TICRRTreslin. (1944 aa)    
Predicted Functional Partners:
TOPBP1
DNA topoisomerase 2-binding protein 1 isoform X1.
    
 
 0.855
CDC45
Cell division control protein 45 homolog.
   
  
 0.765
MTBP
Mdm2-binding protein isoform X1.
   
 0.700
DBF4
Protein DBF4 homolog A isoform X1.
   
  
 0.694
MCM10
Minichromosome maintenance protein 10.
   
  
 0.693
TBL3
U3 small nucleolar RNA-associated protein 13.
   
 
 0.684
WDR36
U3 small nucleolar RNA-associated protein 21.
   
 
 0.676
PWP2
Periodic tryptophan protein 2 homolog.
   
 
 0.665
MCM4
DNA replication licensing factor MCM4.
   
  
 0.655
EXO1
Exonuclease 1.
  
 
 0.651
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.