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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MBTPS1Membrane-bound transcription factor site-1 protease isoform X1. (1060 aa)    
Predicted Functional Partners:
ATF6
Activating transcription factor 6.
     
 0.924
CREB3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3.
     
 0.762
SCAP
Sterol regulatory element-binding protein cleavage-activating protein isoform X1.
   
 
 0.721
SREBF2
Sterol regulatory element-binding transcription factor 2.
     
 0.688
SREBF1
Sterol regulatory element-binding transcription factor 1.
     
 0.688
MBTPS2
Membrane-bound transcription factor site-2 protease isoform X1.
   
  
 0.678
CREB3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1.
     
 0.617
FAM20C
Extracellular serine/threonine protein kinase FAM20C isoform X1.
     
 0.576
FAM20A
Pseudokinase FAM20A.
     
 0.569
CREB3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X1.
     
 0.553
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.