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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERGIC3Endoplasmic reticulum-Golgi intermediate compartment protein 3. (383 aa)    
Predicted Functional Partners:
ERGIC2
Endoplasmic reticulum-Golgi intermediate compartment protein 2 isoform X1.
   
 
0.992
ENSPMJP00000005118
annotation not available
  
 0.904
VPS45
Vacuolar protein sorting-associated protein 45 isoform X1.
 
      0.899
YARS1
Tyrosine--tRNA ligase, cytoplasmic.
     
 0.669
COX18
Mitochondrial inner membrane protein COX18.
  
  
 0.568
EPRS1
Bifunctional glutamate/proline--tRNA ligase isoform X1.
  
  
 0.552
SERGEF
LOW QUALITY PROTEIN: secretion-regulating guanine nucleotide exchange factor.
   
  
 0.539
RER1
Protein RER1.
   
  
 0.539
PCNA
Proliferating cell nuclear antigen.
  
  
 0.475
COPE
Coatomer protein complex subunit epsilon.
   
 
 0.473
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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