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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UFL1E3 UFM1-protein ligase 1. (822 aa)    
Predicted Functional Partners:
DDRGK1
DDRGK domain containing 1.
    
 
 0.935
UBA5
Ubiquitin-like modifier-activating enzyme 5 isoform X1.
   
 
 0.852
UFM1
Ubiquitin-fold modifier 1.
   
 
 0.752
UEVLD
Ubiquitin-conjugating enzyme E2 variant 3 isoform X1.
   
  
 0.710
ATG7
Ubiquitin-like modifier-activating enzyme ATG7 isoform X5.
   
 
 0.638
UBA3
NEDD8-activating enzyme E1 catalytic subunit isoform X1.
     
 0.637
UFSP2
Ufm1-specific protease 2 isoform X1.
   
  
 0.561
PAWR
PRKC apoptosis WT1 regulator protein.
      
 0.533
TRABD
TraB domain-containing protein isoform X1.
   
  
 0.531
SUGT1
Suppressor of G2 allele of SKP1.
      
 0.526
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.