close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMPD3Sphingomyelin phosphodiesterase 3. (660 aa)    
Predicted Functional Partners:
SMPD2
Sphingomyelin phosphodiesterase 2 isoform X1.
     
 0.965
SMPD4
Sphingomyelin phosphodiesterase 4 isoform X1.
     
 0.962
SMPD1
Sphingomyelin phosphodiesterase.
     
 0.951
DEGS1
Sphingolipid 4-desaturase/C4-monooxygenase.
     
 0.925
SGMS2
Phosphatidylcholine:ceramide cholinephosphotransferase 2.
     
 0.923
SGMS1
Phosphatidylcholine:ceramide cholinephosphotransferase 1.
     
 0.923
ASAH1
Acid ceramidase.
     
 0.919
UGCG
Ceramide glucosyltransferase.
     
 0.919
ACER1
Alkaline ceramidase 1 isoform X1.
     
 0.919
DEGS2
Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 isoform X1.
     
 0.918
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.