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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NFE2L3Nuclear factor erythroid 2-related factor 3 isoform X1. (378 aa)    
Predicted Functional Partners:
MAFK
Transcription factor MAFF/G/K.
   
 0.742
GSK3B
Glycogen synthase kinase-3 beta isoform X1.
    
 0.730
CUL3
Cullin 3.
    
 0.707
MAFF
Transcription factor MafF isoform X1.
   
 0.663
CUL1
Cullin-1 isoform X1.
    
 0.637
ENSPMJP00000002807
annotation not available
    
 0.629
KLHL18
Kelch-like protein 18.
    
 0.629
KLHL20
Kelch-like protein 20 isoform X1.
    
 0.629
KLHL17
Kelch-like protein 17 (actinfilin).
    
 0.629
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2 isoform X1.
   
 
 0.619
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.