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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MANEAGlycoprotein endo-alpha-1,2-mannosidase isoform X1. (457 aa)    
Predicted Functional Partners:
GMPS
GMP synthase (glutamine-hydrolysing).
  
 
 0.651
GRIN1
Glutamate receptor ionotropic, NMDA 1 isoform X1.
   
 0.646
AK9
Adenylate kinase 9.
   
 0.592
GART
Trifunctional purine biosynthetic protein adenosine-3.
  
 
 0.585
LOC107200385
Trifunctional purine biosynthetic protein adenosine-3-like isoform X1.
  
 
 0.585
MGAT5B
Mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B.
   
 0.580
ITSN2
Intersectin-2 isoform X1.
    
 0.545
CNKSR3
Connector enhancer of kinase suppressor of ras 3.
    
 
 0.537
APRT
Adenine phosphoribosyltransferase.
  
 
 0.524
LOC107213021
Adenine phosphoribosyltransferase-like.
  
 
 0.524
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.