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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRF1Transcription factor IIIB 90 kDa subunit isoform X1. (681 aa)    
Predicted Functional Partners:
TBP
Transcription initiation factor TFIID TATA-box-binding protein.
   
 0.998
GTF3C3
General transcription factor 3C polypeptide 3 (transcription factor C subunit 4).
    
 0.995
ENSPMJP00000004843
annotation not available
    
 0.994
POLR3F
DNA-directed RNA polymerase III subunit RPC6.
    
 0.984
POLR3B
DNA-directed RNA polymerase III subunit RPC2.
   
 0.970
POLR3A
DNA-directed RNA polymerase III subunit RPC1 isoform X1.
   
 0.967
POLR2K
RNA polymerase II subunit K.
    
 0.948
POLR3C
DNA-directed RNA polymerase III subunit RPC3 isoform X1.
    
 0.947
CRCP
DNA-directed RNA polymerase III subunit RPC9 isoform X1.
    
 0.941
POLR1C
DNA-directed RNA polymerases I and III subunit RPAC1.
    
 0.939
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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