close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NTRK3Neurotrophic tyrosine kinase, receptor type 3. (852 aa)    
Predicted Functional Partners:
PTPRS
Receptor-type tyrosine-protein phosphatase S isoform X1.
    
 0.908
BDNF
Brain-derived neurotrophic factor isoform X1.
   
 0.878
NTF3
Neurotrophin-3 isoform X1.
    
 0.853
PTPRD
Receptor-type tyrosine-protein phosphatase delta isoform X1.
    
 0.832
PTPRF
Receptor-type tyrosine-protein phosphatase F isoform X1.
    
 0.818
NGFR
Tumor necrosis factor receptor superfamily member 16.
   
 0.766
SHC1
SHC-transforming protein 1 isoform X1.
   
 0.693
SHC3
SHC adaptor protein 3.
   
 0.659
GRB2
Growth factor receptor-binding protein 2.
    
 0.647
SQSTM1
Sequestosome-1 isoform X1.
    
 0.635
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.