close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VWA5B2Von Willebrand factor A domain-containing protein 5B2 isoform X1. (1287 aa)    
Predicted Functional Partners:
PARG
Poly(ADP-ribose) glycohydrolase isoform X1.
    
 0.824
FEN1
Flap endonuclease 1.
   
 0.715
XPC
DNA repair protein complementing XP-C cells isoform X1.
    
 0.653
FAAP24
Fanconi anemia core complex-associated protein 24.
     
 0.649
XRCC5
X-ray repair cross-complementing protein 5 isoform X1.
   
 
 0.644
HPF1
Histone PARylation factor 1 isoform X1.
    
 
 0.619
XRCC6
X-ray repair cross-complementing protein 6 isoform X1.
   
 
 0.617
NBN
Nibrin isoform X2.
    
 0.615
XPA
DNA repair protein complementing XP-A cells isoform X1.
     
 0.612
CCNH
Cyclin H.
     
 0.611
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.