close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPMJP00000001833Cytochrome c oxidase assembly factor 4 homolog, mitochondrial isoform X2. (79 aa)    
Predicted Functional Partners:
SDHAF4
Succinate dehydrogenase assembly factor 4, mitochondrial.
      
 0.675
LYRM7
Complex III assembly factor LYRM7 isoform X1.
      
 0.645
CMC2
COX assembly mitochondrial protein 2 homolog.
   
 
 0.611
SLC39A3
Solute carrier family 39 (zinc transporter), member 1/2/3.
      
 0.590
COA6
Cytochrome c oxidase assembly factor 6 homolog.
   
 
 0.586
SSBP1
Single stranded DNA binding protein 1.
    
 
 0.558
COX17
Cytochrome c oxidase assembly protein subunit 17.
    
 0.555
COX19
Cytochrome c oxidase assembly protein subunit 19.
     
 0.536
COQ3
Polyprenyldihydroxybenzoate methyltransferase / 3-demethylubiquinol 3-O-methyltransferase.
      
 0.519
CHCHD4
Mitochondrial intermembrane space import and assembly protein 40.
   
 
 0.513
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: low (22%) [HD]