Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FRAS1Fraser extracellular matrix complex subunit 1. (2275 aa)    
Predicted Functional Partners:
PTPRK
Receptor-type tyrosine-protein phosphatase kappa isoform X1.
   
 0.916
EDN3
Endothelin 3.
      
 0.911
ITGA8
Integrin alpha 8.
   
 
 0.906
ITGB1
Integrin beta-1 isoform X3.
    
  0.901
FREM2
FRAS1-related extracelluar matrix protein 1/2.
   
0.869
NPNT
Nephronectin isoform X1.
   
 0.857
FREM1
FRAS1 related extracellular matrix 1.
   
0.851
GRIP1
Glutamate receptor interacting protein 1.
    
 0.610
PTPRT
Receptor-type tyrosine-protein phosphatase T isoform X1.
   
 0.573
PTPRM
Receptor-type tyrosine-protein phosphatase mu isoform X1.
   
 0.573
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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