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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHLPP1PH domain and leucine-rich repeat-containing protein phosphatase. (1623 aa)    
Predicted Functional Partners:
FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5 isoform X1.
    
 
 0.745
SUGT1
Suppressor of G2 allele of SKP1.
    
 
 0.741
AKT1
RAC-alpha serine/threonine-protein kinase.
    
 0.724
AKT3
RAC-gamma serine/threonine-protein kinase isoform X1.
    
 0.724
FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4.
    
 
 0.714
CAP1
Adenylyl cyclase-associated protein 1 isoform X1.
    
 
 0.700
CAP2
Adenylyl cyclase-associated protein 2.
    
 
 0.700
USP1
Ubiquitin carboxyl-terminal hydrolase 1.
    
 
 0.624
WDR48
WD repeat-containing protein 48.
    
 
 0.602
NPPC
Natriuretic peptide C.
    
 0.514
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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