Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCR6C-C chemokine receptor type 6. (364 aa)    
Predicted Functional Partners:
CCL20
C-C motif chemokine ligand 20.
     
 0.986
CCL19-2
C-C motif chemokine 19.
    
 0.807
IL22
Interleukin 22.
      
 0.794
CD4
T-cell surface glycoprotein CD4 isoform X1.
      
 0.679
IL17A
Interleukin 17A.
      
 0.679
CD83
CD83 antigen.
      
 0.675
CD44
CD44 antigen isoform X1.
     
 0.661
CD40
CD40 molecule.
    
 0.659
IFNG
Interferon gamma.
      
 0.654
ENSPMJP00000016363
annotation not available
      
 0.604
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: low (30%) [HD]