STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APLFAprataxin and PNK-like factor isoform X2. (404 aa)    
Predicted Functional Partners:
LIG3
DNA ligase 3 isoform X1.
    
 
 0.974
LIG4
DNA ligase 4.
    
 
 0.965
XRCC6
X-ray repair cross-complementing protein 6 isoform X1.
    
 
 0.965
PARP1
Poly [ADP-ribose] polymerase 1.
    
 
 0.965
XRCC5
X-ray repair cross-complementing protein 5 isoform X1.
    
 
 0.956
TDP1
Tyrosyl-DNA phosphodiesterase 1 isoform X1.
    
 
 0.951
POLB
DNA polymerase beta isoform X1.
    
 
 0.941
CHD1L
Chromodomain-helicase-DNA-binding protein 1-like.
    
 
 0.937
XPC
DNA repair protein complementing XP-C cells isoform X1.
    
 
 0.919
MACROH2A1
Core histone macro-H2A.1 isoform X1.
    
 
 0.913
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.