close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP2Matrix metalloproteinase-2 (gelatinase A). (659 aa)    
Predicted Functional Partners:
TIMP2
LOW QUALITY PROTEIN: metalloproteinase inhibitor 2.
   
 0.779
TIMP3
Metalloproteinase inhibitor 3.
   
 0.638
MMP7
Matrix metalloproteinase-7 (matrilysin, uterine).
   
0.601
MMP1
Matrix metalloproteinase-1 (interstitial collagenase).
   
 
0.562
OPTC
Opticin.
    
  0.543
SPP1
Secreted phosphoprotein 1.
   
 
 0.526
MMP13
Matrix metalloproteinase-13 (collagenase 3).
   
 
 
0.526
DCN
Decorin.
   
 0.508
MMP15
Matrix metalloproteinase-15 (membrane-inserted).
   
0.488
TIMP4
Metalloproteinase inhibitor 4.
    
 0.440
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.