Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPCS3Signal peptidase complex subunit 3. (180 aa)    
Predicted Functional Partners:
SPCS2
Signal peptidase complex subunit 2.
   
 0.997
SPCS1
Signal peptidase complex subunit 1.
   
 0.996
GRP
Gastrin-releasing peptide.
   
 0.911
SEC11C
Signal peptidase complex catalytic subunit SEC11C isoform X1.
   
 0.911
SEC11A
SEC11 homolog A, signal peptidase complex subunit.
   
 0.911
SEC63
Translocation protein SEC63 homolog.
    
 
 0.897
ASB5
Ankyrin repeat and SOCS box containing 5.
    
 
 0.661
LOC107214352
MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 13.
    
   0.647
LOC107214455
Solute carrier family 22 member 13-like.
    
   0.647
NIFK
MKI67 FHA domain-interacting nucleolar phosphoprotein isoform X1.
      
 0.627
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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