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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PICALMPhosphatidylinositol-binding clathrin assembly protein isoform X1. (712 aa)    
Predicted Functional Partners:
GAK
Cyclin-G-associated kinase isoform X1.
   
 0.983
ITSN2
Intersectin-2 isoform X1.
    
 0.970
ITSN1
Intersectin-1 isoform X1.
    
 0.958
AP2M1
AP-2 complex subunit mu isoform X1.
    
 0.750
UBA52
Ubiquitin-large subunit ribosomal protein L40e.
    
  0.747
RPS27A
Ubiquitin-small subunit ribosomal protein S27Ae.
    
 0.747
STON2
Stonin-1/2.
    
 0.695
ENSPMJP00000011085
annotation not available
     
 0.681
SORL1
Sortilin related receptor 1.
     
 0.681
ENSPMJP00000027002
Ubiquitin.
    
 0.681
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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