close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL10Interleukin 10. (370 aa)    
Predicted Functional Partners:
IL10RA
Interleukin-10 receptor subunit alpha.
    
 0.965
IL6
Interleukin 6.
   
 
 0.938
IL10RB
Interleukin-10 receptor subunit beta-like.
    
 0.896
IFNG
Interferon gamma.
   
  
 0.816
CD4
T-cell surface glycoprotein CD4 isoform X1.
   
 
 0.805
LOC107213896
Interleukin-1 receptor antagonist protein-like.
   
 
 0.798
IL18
Interleukin-18-like.
   
 
 0.776
TNFSF15
TNF superfamily member 15.
   
 
 0.746
IL22
Interleukin 22.
   
  
 0.708
IL17A
Interleukin 17A.
   
 
 0.699
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.