close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC107215667Keratin, type II cytoskeletal 8. (498 aa)    
Predicted Functional Partners:
UBE2V1
Ubiquitin-conjugating enzyme E2 variant 1.
   
 0.904
BAG3
BAG family molecular chaperone regulator 3.
    
 0.670
RPS27A
Ubiquitin-small subunit ribosomal protein S27Ae.
    
  0.617
UBA52
Ubiquitin-large subunit ribosomal protein L40e.
   
  0.602
NBR1
Next to BRCA1 gene 1 protein isoform X1.
    
 0.591
LOC107215678
Keratin, type II cytoskeletal cochleal.
  
0.570
TSC1
Tuberous sclerosis 1.
    
 0.560
TRAP1
Heat shock protein 75 kDa, mitochondrial.
    
 0.560
HSP90AB1
LOW QUALITY PROTEIN: heat shock protein HSP 90-beta.
    
 0.560
HSP90AA1
Heat shock protein HSP 90-alpha.
    
 0.560
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: low (30%) [HD]