STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EZH1[histone H3]-lysine27 N-trimethyltransferase EZH1. (744 aa)    
Predicted Functional Partners:
SUZ12
Polycomb protein SUZ12.
   
 0.974
EED
Polycomb protein EED.
    
 0.968
RBBP4
Histone-binding protein RBBP4.
    
 0.954
AEBP2
AE binding protein 2.
   
 0.926
JARID2
Protein Jumonji isoform X1.
   
 0.926
PHF19
PHD finger protein 19 isoform X1.
   
 0.923
MTF2
Metal-response element-binding transcription factor 2 isoform X1.
   
 0.923
RBBP7
RB binding protein 7, chromatin remodeling factor.
    
 0.875
KDM6A
Lysine-specific demethylase 6A isoform X1.
   
 0.836
CBX8
Chromobox protein homolog 8 isoform X1.
    
 0.795
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.