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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPMJP00000002425annotation not available (464 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK1.
   
 0.718
PLK2
Serine/threonine-protein kinase PLK2.
   
 0.646
PLK3
Polo like kinase 3.
   
 0.646
BORA
Protein aurora borealis isoform X1.
     
 0.552
CDK11A
Cyclin dependent kinase 11A.
   
 
  0.550
TMEM82
Transmembrane protein 82.
      
 0.533
AURKA
Aurora kinase A.
   
 0.506
NTAN1
N-terminal asparagine amidase.
      
 0.470
CDK10
Cyclin dependent kinase 10.
   
 
  0.429
HAUS1
HAUS augmin-like complex subunit 1 isoform X1.
    
  0.422
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.