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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DROSHARibonuclease III. (1336 aa)    
Predicted Functional Partners:
DGCR8
Microprocessor complex subunit DGCR8.
   
 0.994
AGO2
Eukaryotic translation initiation factor 2C.
   
 0.853
DDX5
Probable ATP-dependent RNA helicase DDX5 isoform X1.
  
 
 0.830
ENSPMJP00000000984
annotation not available
    
 0.812
LOC107209537
RISC-loading complex subunit TARBP2-like.
    
 0.812
MRPS9
28S ribosomal protein S9, mitochondrial isoform X1.
   
 
 0.803
DDX17
Probable ATP-dependent RNA helicase DDX17 isoform X1.
  
 
 0.792
MRPL27
39S ribosomal protein L27, mitochondrial.
  
 
 0.790
MRPL20
39S ribosomal protein L20, mitochondrial.
  
 
 0.785
MRPS6
28S ribosomal protein S6, mitochondrial.
   
 
 0.783
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.