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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RUNDC1RUN domain-containing protein 1 isoform X1. (546 aa)    
Predicted Functional Partners:
PTGES3L
Putative protein PTGES3L.
      
 0.683
VPS51
Vacuolar protein sorting-associated protein 51 homolog.
   
  
 0.563
CCDC186
Coiled-coil domain-containing protein 186 isoform X2.
      
 0.541
VPS53
Vacuolar protein sorting-associated protein 53 homolog isoform X1.
      
 0.531
ICA1
Islet cell autoantigen 1 isoform X1.
    
 
 0.488
VPS54
VPS54 subunit of GARP complex.
      
 0.465
TMF1
TATA element modulatory factor.
      
 0.465
EIPR1
EARP and GARP complex-interacting protein 1.
      
 0.455
ENSPMJP00000002489
annotation not available
      
 0.434
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.