close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SECISBP2Selenocysteine insertion sequence-binding protein 2 isoform X1. (847 aa)    
Predicted Functional Partners:
HSPA5
Endoplasmic reticulum chaperone BiP.
  
 0.794
CALR
Calreticulin.
   
 0.754
EEFSEC
Selenocysteine-specific elongation factor.
    
 0.666
ERO1B
ERO1-like protein beta.
   
 0.637
ERO1A
Endoplasmic reticulum oxidoreductase 1 alpha.
   
 0.637
RPL30
Large subunit ribosomal protein L30e.
    
 0.622
GPS1
COP9 signalosome complex subunit 1.
   
 0.618
DLD
Dihydrolipoyl dehydrogenase, mitochondrial.
  
 0.602
CLGN
Calmegin isoform X1.
   
 0.580
CANX
Calnexin.
   
 0.580
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.