close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RTN1Reticulon-1 isoform X1. (758 aa)    
Predicted Functional Partners:
SEC63
Translocation protein SEC63 homolog.
    
 
 0.707
VTA1
Vacuolar protein sorting-associated protein VTA1 homolog isoform X2.
    
   0.541
GCH1
GTP cyclohydrolase IA.
    
   0.541
OMG
Oligodendrocyte myelin glycoprotein.
    
 0.500
NGFR
Tumor necrosis factor receptor superfamily member 16.
     
 0.498
LNPK
Endoplasmic reticulum junction formation protein lunapark.
    
 
 0.467
LINGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein.
   
 0.461
TMEM33
Transmembrane protein 33.
    
 
 0.438
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.