MAP2K7 protein (Parus major) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

MAP2K7

Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (665 aa)

Predicted Functional Partners:

MAP3K1

0.995

MAPK10

0.994

MAPK8

0.994

MAPK8IP1

0.992

MAP3K7

0.991

MAPK9

0.989

MAP2K4

0.988

MAP3K20

0.979

MAPK8IP3

0.973

MAP3K5

0.953

Your Current Organism:

Parus major

NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAP2K4	MAP2K7	ENSPMJP00000025619	ENSPMJP00000002814	Dual specificity mitogen-activated protein kinase kinase 4.	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1.	0.988
MAP2K4	MAP3K1	ENSPMJP00000025619	ENSPMJP00000021631	Dual specificity mitogen-activated protein kinase kinase 4.	Mitogen-activated protein kinase kinase kinase 1 isoform X1.	0.997
MAP2K4	MAP3K20	ENSPMJP00000025619	ENSPMJP00000025350	Dual specificity mitogen-activated protein kinase kinase 4.	Mitogen-activated protein kinase kinase kinase MLT isoform X1.	0.779
MAP2K4	MAP3K5	ENSPMJP00000025619	ENSPMJP00000009912	Dual specificity mitogen-activated protein kinase kinase 4.	Mitogen-activated protein kinase kinase kinase 5.	0.949
MAP2K4	MAP3K7	ENSPMJP00000025619	ENSPMJP00000001792	Dual specificity mitogen-activated protein kinase kinase 4.	Mitogen-activated protein kinase kinase kinase 7 isoform X1.	0.994
MAP2K4	MAPK10	ENSPMJP00000025619	ENSPMJP00000011441	Dual specificity mitogen-activated protein kinase kinase 4.	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase).	0.996
MAP2K4	MAPK8	ENSPMJP00000025619	ENSPMJP00000021583	Dual specificity mitogen-activated protein kinase kinase 4.	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase).	0.996
MAP2K4	MAPK8IP3	ENSPMJP00000025619	ENSPMJP00000010344	Dual specificity mitogen-activated protein kinase kinase 4.	C-Jun-amino-terminal kinase-interacting protein 3 isoform X1.	0.950
MAP2K4	MAPK9	ENSPMJP00000025619	ENSPMJP00000011209	Dual specificity mitogen-activated protein kinase kinase 4.	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase).	0.998
MAP2K7	MAP2K4	ENSPMJP00000002814	ENSPMJP00000025619	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1.	Dual specificity mitogen-activated protein kinase kinase 4.	0.988
MAP2K7	MAP3K1	ENSPMJP00000002814	ENSPMJP00000021631	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1.	Mitogen-activated protein kinase kinase kinase 1 isoform X1.	0.995
MAP2K7	MAP3K20	ENSPMJP00000002814	ENSPMJP00000025350	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1.	Mitogen-activated protein kinase kinase kinase MLT isoform X1.	0.979
MAP2K7	MAP3K5	ENSPMJP00000002814	ENSPMJP00000009912	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1.	Mitogen-activated protein kinase kinase kinase 5.	0.953
MAP2K7	MAP3K7	ENSPMJP00000002814	ENSPMJP00000001792	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1.	Mitogen-activated protein kinase kinase kinase 7 isoform X1.	0.991
MAP2K7	MAPK10	ENSPMJP00000002814	ENSPMJP00000011441	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1.	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase).	0.994
MAP2K7	MAPK8	ENSPMJP00000002814	ENSPMJP00000021583	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1.	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase).	0.994
MAP2K7	MAPK8IP1	ENSPMJP00000002814	ENSPMJP00000019169	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1.	Mitogen-activated protein kinase 8 interacting protein 1.	0.992
MAP2K7	MAPK8IP3	ENSPMJP00000002814	ENSPMJP00000010344	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1.	C-Jun-amino-terminal kinase-interacting protein 3 isoform X1.	0.973
MAP2K7	MAPK9	ENSPMJP00000002814	ENSPMJP00000011209	Dual specificity mitogen-activated protein kinase kinase 7 isoform X1.	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase).	0.989
MAP3K1	MAP2K4	ENSPMJP00000021631	ENSPMJP00000025619	Mitogen-activated protein kinase kinase kinase 1 isoform X1.	Dual specificity mitogen-activated protein kinase kinase 4.	0.997