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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTC14Tetratricopeptide repeat protein 14. (688 aa)    
Predicted Functional Partners:
PNISR
Arginine/serine-rich protein PNISR isoform X1.
   
   0.630
DNAJC19
Mitochondrial import inner membrane translocase subunit TIM14.
      
 0.546
MBTPS2
Membrane-bound transcription factor site-2 protease isoform X1.
      
 0.539
SERINC2
Serine incorporator 2 isoform X1.
    
 
 0.520
ZFC3H1
Zinc finger C3H1 domain-containing protein isoform X1.
   
   0.491
POLR2B
DNA-directed RNA polymerase II subunit RPB2.
    
 
 0.480
FXR1
Fragile X mental retardation syndrome-related protein 1 isoform X1.
   
 
 0.476
MCCC1
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial.
      
 0.467
CLDN18
Claudin-18.
      
 0.461
RNPC3
U11/U12 small nuclear ribonucleoprotein 65 kDa protein.
   
   0.460
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.