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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKA1Spindle and kinetochore-associated protein 1. (274 aa)    
Predicted Functional Partners:
SKA3
Spindle and kinetochore-associated protein 3 isoform X1.
   
 
 0.967
SKA2
Spindle and kinetochore-associated protein 2.
   
 
 0.960
CDC20
Cell division cycle 20, cofactor of APC complex.
   
 
 0.774
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 
 0.770
NUF2
Kinetochore protein Nuf2.
   
  
 0.753
CDK1
Cyclin-dependent kinase 1.
   
 
 0.752
PLK1
Serine/threonine-protein kinase PLK1.
   
 
 0.736
BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1 isoform X1.
   
 
 0.733
KIF11
Kinesin-like protein KIF11 isoform X1.
   
  
 0.731
MAD2L1
Mitotic spindle assembly checkpoint protein MAD2A.
   
 
 0.721
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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