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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACTL6AActin-like protein 6A. (429 aa)    
Predicted Functional Partners:
ARID4A
AT-rich interaction domain 4A.
   
 0.993
ARID4B
AT-rich interactive domain-containing protein 4B isoform X2.
   
 0.993
SMARCB1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1.
   
 0.963
RUVBL1
RuvB-like protein 1 (pontin 52).
   
 0.960
ACTR8
Actin-related protein 8.
    
0.951
ITSN2
Intersectin-2 isoform X1.
   
 
 0.944
DMAP1
DNA methyltransferase 1-associated protein 1.
   
 0.930
RUVBL2
RuvB-like protein 2.
   
 0.928
PBRM1
Protein polybromo-1 isoform X1.
   
 0.909
ACTR5
LOW QUALITY PROTEIN: actin-related protein 5.
    
0.896
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.