Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WNT4Wingless-type MMTV integration site family, member 4. (368 aa)    
Predicted Functional Partners:
WLS
Protein wntless homolog.
    
 0.921
FZD6
Frizzled 6.
    
 0.908
FZD3
Frizzled 3.
    
 0.883
LRP6
Low-density lipoprotein receptor-related protein 6 isoform X1.
    
 0.880
LRP5
Low-density lipoprotein receptor-related protein 5 isoform X1.
    
 0.865
FZD4
Frizzled 4.
    
 0.849
SFRP1
Secreted frizzled-related protein 1.
    
 0.843
SFRP2
Secreted frizzled-related protein 2.
    
 0.820
FZD7
Frizzled 1/7.
    
 0.817
WIF1
WNT inhibitory factor 1.
    
 0.814
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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