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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDC42SE2CDC42 small effector protein 2. (84 aa)    
Predicted Functional Partners:
HSPA5
Endoplasmic reticulum chaperone BiP.
  
 0.708
HSP90B1
Heat shock protein 90kDa beta.
  
 0.645
CDC42
Cell division control protein 42 homolog isoform X1.
    
 0.598
HSPA9
Stress-70 protein, mitochondrial.
  
 0.577
HYOU1
Hypoxia up-regulated protein 1.
  
 0.566
BAIAP2L1
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 isoform X1.
    
 0.543
CDC42EP4
Cdc42 effector protein 4.
      
 0.533
CLPB
ATP-dependent Clp protease ATP-binding subunit ClpB.
  
 
 0.530
TSC1
Tuberous sclerosis 1.
  
 0.525
TRAP1
Heat shock protein 75 kDa, mitochondrial.
  
 0.525
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.