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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IDEInsulin-degrading enzyme isoform X1. (1024 aa)    
Predicted Functional Partners:
INS
Insulin.
    
 0.953
APP
Amyloid beta A4 protein isoform X1.
    
 
 0.914
RPS27A
Ubiquitin-small subunit ribosomal protein S27Ae.
    
 0.870
UBA52
Ubiquitin-large subunit ribosomal protein L40e.
    
  0.861
IGF2
Insulin-like growth factor II.
    
 
 0.820
LOC107212843
C-C motif chemokine 4 homolog.
    
   0.809
ENSPMJP00000027002
Ubiquitin.
    
  0.739
NPPB
Natriuretic peptides A.
    
 
 0.710
TOMM70
Mitochondrial import receptor subunit TOM70.
   
 
 0.679
PHEX
Phosphate-regulating neutral endopeptidase isoform X1.
      
 0.678
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.