Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
IKBKGInhibitor of nuclear factor kappa-B kinase subunit gamma. (447 aa)    
Predicted Functional Partners:
CHUK
Inhibitor of nuclear factor kappa-B kinase subunit alpha.
   
 0.980
IKBKB
Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.
   
 0.976
BCL10
B-cell lymphoma/leukemia 10.
    
 0.976
TAB3
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1.
    
 0.957
TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2.
    
 0.954
TRAF6
TNF receptor-associated factor 6.
    
 0.953
TANK
TRAF family member-associated NF-kappa-B activator isoform X1.
    
 0.949
MAP3K7
Mitogen-activated protein kinase kinase kinase 7 isoform X1.
    
 0.943
MAP3K1
Mitogen-activated protein kinase kinase kinase 1 isoform X1.
    
 0.940
RIPK1
Receptor-interacting serine/threonine-protein kinase 1 isoform X1.
    
 0.940
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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