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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL18Kelch-like protein 18. (577 aa)    
Predicted Functional Partners:
CUL3
Cullin 3.
    
 0.851
NFE2L2
Nuclear factor erythroid 2-related factor 2 isoform X1.
    
 0.824
SQSTM1
Sequestosome-1 isoform X1.
    
 0.795
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.766
NFE2L3
Nuclear factor erythroid 2-related factor 3 isoform X1.
    
 0.629
NFE2L1
Nuclear factor erythroid 2-related factor 1 isoform X1.
    
 0.629
BBS9
Bardet-Biedl syndrome 9 protein.
    
 0.611
BBS4
Bardet-Biedl syndrome 4 protein isoform X1.
    
 0.599
BBS7
Bardet-Biedl syndrome 7 protein isoform X1.
   
 0.562
CUL1
Cullin-1 isoform X1.
    
 0.562
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.