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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOOK3Protein Hook homolog 3 isoform X1. (748 aa)    
Predicted Functional Partners:
DYNC1LI1
Cytoplasmic dynein 1 light intermediate chain 1.
    
 0.882
AKTIP
AKT-interacting protein isoform X1.
   
 
 0.748
BICD2
Protein bicaudal D homolog 2 isoform X1.
    
 
 0.738
RAB11FIP3
Rab11 family-interacting protein 3 isoform X1.
      
 0.690
MCM4
DNA replication licensing factor MCM4.
   
 
 0.671
DYNC1LI2
Cytoplasmic dynein 1 light intermediate chain 2.
    
 0.637
CEP120
Centrosomal protein of 120 kDa isoform X1.
    
 0.598
FAM160A2
Family with sequence similarity 160 member A2.
    
 0.571
FAM160A1
Protein FAM160A1.
    
 0.571
NUDC
Nuclear migration protein nudC.
   
  
 0.566
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.