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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OMA1Metalloendopeptidase OMA1, mitochondrial isoform X1. (558 aa)    
Predicted Functional Partners:
YME1L1
ATP-dependent zinc metalloprotease YME1L1 isoform X1.
  
 
 0.772
OPA1
OPA1 mitochondrial dynamin like GTPase.
     
 0.757
MYSM1
Histone H2A deubiquitinase MYSM1 isoform X1.
   
 
 0.692
ATP23
Mitochondrial inner membrane protease ATP23 homolog isoform X1.
    
 
 0.689
CLPB
ATP-dependent Clp protease ATP-binding subunit ClpB.
  
  
 0.683
AFG3L2
AFG3-like protein 2 isoform X1.
  
 
 0.678
ZMPSTE24
CAAX prenyl protease 1 homolog isoform X1.
      
 0.629
HSPE1
Heat shock protein family E (Hsp10) member 1.
  
  
 0.625
SPG7
Spastic paraplegia 7.
  
 
 0.616
GRPEL2
GrpE protein homolog 2, mitochondrial.
  
  
 0.580
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.