Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TMEM175Endosomal/lysomomal potassium channel TMEM175. (576 aa)    
Predicted Functional Partners:
LAMP1
Lysosome-associated membrane glycoprotein 1.
    
 
 0.796
ATP13A2
ATPase cation transporting 13A2.
      
 0.693
DGKQ
Diacylglycerol kinase (ATP).
      
 0.685
TVP23A
Golgi apparatus membrane protein TVP23 homolog A.
      
 0.636
TMEM230
Transmembrane protein 230.
      
 0.551
TMEM275
Transmembrane protein 275.
      
 0.549
TMEM17
Transmembrane protein 17 isoform X1.
      
 0.546
PCGF3
Polycomb group RING finger protein 3 isoform X1.
      
 0.542
SAMD5
Sterile alpha motif domain containing 5.
      
 0.473
SIPA1L2
Signal-induced proliferation-associated 1-like protein 2 isoform X1.
      
 0.451
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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