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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATP2A2Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1. (1043 aa)    
Predicted Functional Partners:
PLN
Cardiac phospholamban isoform X2.
   
 0.992
ATP2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3.
  
 
 
0.902
ENSPMJP00000023758
annotation not available
  
 
 0.762
ATP2B2
Plasma membrane calcium-transporting ATPase 2 isoform X1.
  
 
0.619
ATP2B1
Plasma membrane calcium-transporting ATPase 1 isoform X3.
  
 
0.617
TNNC2
Troponin C, skeletal muscle.
   
 
 0.592
TNNI2
Troponin I, fast skeletal muscle.
   
 0.573
SOX5
Transcription factor SOX5/6/13 (SOX group D).
      
 0.565
SLC8A1
Solute carrier family 8 (sodium/calcium exchanger).
    
 
 0.554
EEF2
Elongation factor 2.
   
  
 0.554
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.