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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TM2D1TM2 domain containing 1. (191 aa)    
Predicted Functional Partners:
TM2D2
TM2 domain-containing protein 2.
   
  
 0.683
TRDMT1
TRNA (cytosine(38)-C(5))-methyltransferase isoform X1.
      
 0.598
C2CD2
C2 domain-containing protein 2.
      
 0.546
FAM92A
Protein FAM92A1 isoform X1.
      
 0.541
LOC107204426
Endonuclease domain-containing 1 protein-like.
      
 0.533
NHLRC2
NHL repeat-containing protein 2.
      
 0.531
LAMTOR3
Ragulator complex protein LAMTOR3.
      
 0.520
FBXO4
F-box only protein 4.
   
  
 0.478
NPRL2
NPR2 like, GATOR1 complex subunit.
   
  
 0.471
CCDC86
Coiled-coil domain-containing protein 86.
      
 0.461
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.