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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LNPEPLeucyl-cystinyl aminopeptidase isoform X1. (1024 aa)    
Predicted Functional Partners:
AGT
Angiotensinogen isoform X1.
  
 0.605
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase isoform X1.
  
  
 0.545
BLMH
Bleomycin hydrolase.
    
 0.520
B2M
Beta-2-microglobulin.
   
 
 0.518
RPA2
Replication protein A 32 kDa subunit.
   
 
 0.502
ENSPMJP00000018190
annotation not available
     
 0.480
TBC1D4
TBC1 domain family member 4 isoform X2.
     
 0.480
TBC1D1
TBC1 domain family member 1 isoform X1.
     
 0.480
CD4
T-cell surface glycoprotein CD4 isoform X1.
     
 0.467
ENSPMJP00000004421
Class I histocompatibility antigen, F10 alpha chain-like.
    
 0.459
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.