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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZMIZ1Zinc finger MIZ domain-containing protein 1 isoform X1. (1043 aa)    
Predicted Functional Partners:
KCTD2
BTB/POZ domain-containing protein KCTD2/5/17.
    
 0.744
UBE2I
Ubiquitin-conjugating enzyme E2 I.
    
 0.744
SUMO1
Small ubiquitin-related modifier 1.
    
 0.732
SUMO2
Small ubiquitin-related modifier 2.
    
 0.689
LOC107208897
Small ubiquitin-related modifier 3-like.
    
 0.689
BARD1
BRCA1-associated RING domain protein 1 isoform X1.
    
 0.636
BIRC6
Baculoviral IAP repeat-containing protein 6 isoform X1.
    
 0.601
PCNA
Proliferating cell nuclear antigen.
   
 
 0.582
POLR3A
DNA-directed RNA polymerase III subunit RPC1 isoform X1.
    
 
 0.533
NSMCE2
E3 SUMO-protein ligase NSE2 isoform X1.
    
 
 0.529
Your Current Organism:
Parus major
NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.